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in terms of the mechanism of its antiviral properties, amantadine interferes with a viral protein, m2 an ion channel , 14 which is required for the viral particle to become uncoated once it is taken inside the cell by endocytosis.
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suicide attempts, some of which have been fatal, have been reported in patients treated with amantadine hydrochloride, many of whom received short courses for influenza treatment or prophylaxis.
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